The center was approved by the Jilin Provincial Development and Reform Commission in December 2012, and has passed continuous assessments and evaluations. The aim is to explore and utilize microbial germplasm resources, as well as microbiology, functional genetics, proteomics, and metabolomics. Professor Pan Hongyu is the director of the laboratory. There are 6 senior researchers with doctoral degrees, 9 intermediate researchers with doctoral degrees, and 16 junior researchers with doctoral and master's degree candidates. He is currently undertaking the National Natural Science Foundation project "Sclerotium sclerotiorum transcription factor". SsNsd1 and SsFdh1 Protein Interaction Mechanism and Regulation Research" (31972978) and other national-level topics include 9 national-level topics, 13 provincial-level topics, and main research directions include:

1. Mining of microbial resources and their functional genes

Use the principles and methods of Metagenomics, Function genomics and Microbiome to mine resource microorganisms, study their functional genes, construct engineered strains, regulate the expression of key biological activity enzyme genes, and study their microbiomes Science and metabolomics, effectively discovering and utilizing microbial resources.

2. Research and develop high-efficiency and multifunctional microbial flora and its preparations

Screening strains with special catalytic purposes from microorganisms to catalyze the biotransformation of some drugs or active compounds; highly specific biological enzymes can also catalyze certain chemical reactions in vitro; at the same time, screening can be environmentally friendly Strains that can transform and degrade harmful substances such as pesticide residues and heavy metals are used as engineered bacteria to improve soil or water quality; build effective microorganisms, namely EM bacteria (Effective microorganisms), which are popularized and applied in agricultural pest control.

3. Currently potent active metabolites and drug lead compounds

Microbial metabolites have novel and varied structures and diverse activities. High-throughput screening of medicinal active strains, antibacterial or insecticidal active strains can also be directly used to develop biological pesticides; tracking and isolating active compounds from the fermentation products of active strains, identifying and constructing them, directly or as a lead compound for further development. Kind of biological pesticides.