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张世宏

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基本情况


    张世宏   博士,教授,博士生导师

吉林大学植物科学学院学术委员会主任(2006年-2015年),吉林大学植物科学学院学术委员会、学位委员会委员(2006年-至今)。

吉林大学 植物抗逆基因工程学术带头人,国家转基因植物中试与产业化基地(吉林)吉林大学卫星实验室(吉林省植物分子生物学研究室)主任, 吉林省作物基因工程重点实验室主任。

 

 

 

 

联系方式

电话:0431-87835708

传真:0431-87835708

E-mail: zhang_sh@jlu.edu.cn

通讯地址:长春市西安大路5333号,吉林大学植物科学学院,邮编 130062

 

教育经历

2000/09-2003/07, 中国农业大学,植物保护学院植病系,博士

1997/09-2000/07, 山东农业大学,植物保护学院植病系,硕士

1989/09-1993/07, 山东农业大学,园艺系果树学,学士

 

工作经历

1. 2012/12-至今,吉林大学,植物科学学院,教授

2. 2011/12-2012/11,普渡大学,生物系,访问学者

3. 2010/12-2011/11,吉林大学,植物科学学院,教授

4. 2010/10-2010/11,密西根大学,植物病理学系,高访

5. 2009/08-2010/09,麻塞诸塞州立大学,生化与分子生物学系,访问教授

6. 2009/10-2010/07,香港中文大学,生命科学学院,访问教授

7. 2006/07-2009/09,吉林大学,植物科学学院,教授

8. 2005/06-2006/06,香港中文大学,生物系,研究员(引进大陆优秀人才计划)

9. 2003/07-2005/05,中国农业大学,农业生物技术国家重点实验室,博士后

 


主要学术兼职

1. 全国农业转基因生物安全管理标准化技术委员会,委员(2017-2022年)

2. 中国农业科学,编委(2017年-至今)

3. 植物学研究,编委(2012年-至今),

4. 美国微生物学会高级会员(2010年-至今)

5. 欧洲植物病理学会会员(2008年-至今)

6. 教育部科技论文在线,特聘专家(2010年-至今)

7. 吉林省植物病理学学会,常务理事(2012-至今)

8. 中国青年植物病理学会,副主任(2008-2014)

9. 中国农业国际合作促进会专家顾问团成员(2017-至今)

10. “一带一路植保国际联盟,理事(2016-至今)

11. 科技部科技奖励计划,评审专家(2008年-至今)

12. 教育部科技奖励计划,评审专家(2008年-至今)

13. 三峡大学生物技术研究中心学术委员会,委员(2015年-至今)

 

 

教学情况

本科生必修课程《农业植物病理学A

硕士研究生必修课程《分子植物病理学》

硕士研究生选修课程《植物基因工程原理》

博士研究生必修课程《高级植物生理生化》

博士研究生选修课程《植物抗逆基因工程》

 

主要研究方向

1、分子植物病理学与植物抗逆基因工程

2、真菌分子遗传学

3、农业微生物遗传与应用

 

代表性课题

1.国家重点研发计划项目,2016YFD0300700,粮食主产区主要病虫草害发生及其绿色防控关键技术子课题,2016.07-2020.12,主持

2.国家自然科学基金面上项目,31671972,稻瘟菌Lon酶切修饰的C3HC-锌指蛋白在线粒体致病途径中的作用机理,2017.01-2020.12 ,主持

3.国家自然科学基金面上项目,31670141,蛋白质-酪氨酸磷酸酶在调控稻瘟菌致病与抗氧化过程中的分子机理,2017.01-2020. 12,第一参加人

4.国家自然科学基金,31201465Lon 蛋白酶介导线粒体参与稻瘟菌致病过程的生化基础研究,2013/01-2015/12 ,主持

5.国家自然科学基金面上项目,31171794BBP/SF1剪接因子参与调控稻瘟菌侵染性菌丝扩展的机理研究,2012/01-2015/12 ,主持

6.农业部植保行业科技项目,201203014,粮食作物基因对基因病害的抗病品种布局技术研究示范,2012/01-2016/12

7.农业部转基因重大专项课题,2011ZX08003-001,抗病虫、抗除草剂转基因玉米新品种培育(子课题),2012.01-2016.12,主持

8.国家自然科学基金面上项目,308716079, 中国东北地区极端低温对稻瘟病菌的选择与致变效应,2009/01-2011/12,主持

9.教育部高等学校博士学科点专项科研基金(博导类),20100061110074,稻瘟菌染色质共价修饰对致病力变异的调控研究,2010/01-2013/12,主持

10.农业部转基因重大专项课题(子课题),植物抗逆基因与逆境诱导性启动子的克隆与功能验证,2009ZX08009-062B2009.1-2010.12,主持

11.农业部植保行业科技项目,200803008,水稻抗瘟性品种布局与稻瘟病防控技术,2008/01-2012/12

 

 

代表性论文

1Xin Zhang 1, Zhengqun Li 2, Yanxiang Zhao 3, Xilan Cheng 1, Yang Liu 1, Shihong Zhang 2,*

and Junfeng Liu 1,* Crystal Structure of a Putative Modulator of Gyrase(TldE) from Thermococcus kodakarensis Crystals 2019, 9, 107; doi:10.3390/cryst9020107

2、 Li ZQ, Wei Y., Pei X., Chen LN., Zhang ZY., Zhang S-H*. The unique GH5 cellulase member in the extreme halophilic fungus Aspergillus glaucus CCHA is an endoglucanase with multiple resistances to saline, alkali and heat: prospects for straw degradation applications. Extremophiles, 2018 (in press)

3、Wei Y, Zhang S-H*. Abiostress resistance and cellulose degradation abilities of haloalkaliphilic fungi: applications for saline-alkaline remediation. Extremophiles, 2018, 22: 155–164. 10.1007/s00792-017-0986-33.  

4、Cui, X., Wei, Y., Xie, X-L., Chen, L-N., Zhang, S-H*. Mitochondrial and peroxisomal Lon proteases play opposing roles in reproduction and growth but co-function in the normal development, stress resistance and longevity of Thermomyces lanuginosus. Fungal Genetics and Biology, 2017, 103: 42–54. doi: http://dx.doi.org/10.1016/j.fgb.2017.04.002.

5、Li, F., Long, L., Yan, W. Li C., Xu J., Liu Y., Zhang S*. Development of an Event-Specific Detection Method for Genetically Modified Maize IE034 by Quantitative Real-Time PCR. Food Anal. Methods.2016. doi:10.1007/s12161-016-0707-z  

6、Pei X, Fan F, Lin L, Chen Y, Sun W, Zhang S*, Tian C. Involvement of the of the adaptor protein 3 complex in lignocellulase secretion in Neurospora crassa revealed by comparative genomic screening. Biotechnology Biofuels. 2015, 8: 124.

7、Cui X, Wei Y, Wang Y, Zheng Y, Li J, Wong F, Liu S, Yan H, Jia B, Liu J, Zhang S*. Proteins interacting with mitochondrial ATP-dependent Lon protease (MAP1) in Magnaporthe oryzae are involved in rice blast disease. Molecular Plant Pathology. 2015, 16(8):847-859.

8、Liu X, Wei Y, Zhou X, Pei X, Zhang S*. Aspergillus glaucus aquaglyceroporin gene glpF confers high osmosis tolerance in heterologous organisms. Applied and Environmental Microbiology. 2015, 81(19): 6926-6937.

9、Liu Y, Xie L, Liang X, Zhang S*. CpLEA5, the late embryogenesis abundant protein gene from Chimonanthus praecox, possesses low temperature and osmotic resistances in prokaryote and eukaryotes. International Journal of Molecular Sciences. 2015, 16, 26978–26990.

10、Pei X, Zhao J, Cai P, Sun W, Ren J, Wu Q, Zhang S, Tian C *. Heterologous expression of a GH3 ß-glucosidase from Neurospora crassa in Pichia pastoris with high purity and its application in the hydrolysis of soybean isoflavone glycosides. Protein Expression and Purification. 2015, 119(2016):75-84.

11、Liang X, Liu Y, Xie L, Liu X, Wei Y, Zhou X, Zhang S*. A ribosomal protein AgRPS3aE from halophilic Aspergillus glaucus confers salt tolerance in heterologous organisms. International Journal of Molecular sciences. 2015, 16(2), 3058-3070.

12、Liang X, Liu J, Liu S, Liang X, Zhang S*. Alternatively spliced SMN orthologue in Magnaporthe oryzae is required for stress resistance and disease development. European Journal of Plant Pathology. 2015, 142:427-439.

13、Li J, Liang X, Wei Y, Liu J, Lin F, Zhang S*. An ATP-dependent protease homolog ensures basic standards of survival and pathogenicity for Magnaporthe oryzae. European Journal of Plant Pathology. 2015, 141(4):703-716.  

14、Pei X, Fan F, Lin L, Chen Y, Sun W, Zhang S*, Tian C. Involvement of the of the adaptor protein 3 complex in lignocellulase secretion in Neurospora crassa revealed by comparative genomic screening. Biotechnology Biofuels. 2015, 8: 124.

15、Liu X, Xie L, Wei Y, Zhou X, Jia B, Liu J, Zhang S*. Abiotic stress resistance, a novel moonlighting function of ribosomal protein RPL44 in halophilic Aspergillus glaucus. Applied and Environmental Microbiology. 2014, 80(14):4294-4300.

16、Li F, Yan W, Long L, Qi X, Li C, Zhang S*. Development and application of loop-mediated isothermal amplification assays for rapid visual detection of cry2Ab and cry3A genes in genetically-modified crops. International Journal of Molecular Sciences. 2014, 15, 15109-15121.

17、Li J, Jia B, Liang X, Liu J, Wang Y, Liang X, Yan H, Wang Y, Zhang S*. An adenosine kinase in apoplastic location is involved in Magnaporthe oryzae cold acclimation. Journal of Basic Microbiology. 2014, 54(4):269-277.

18、Wang F, Liu J, Li J, Zhang S, Pan H*. Functional analyses of the maize CKS2 gene promoter in response to abiotic stresses and hormonesActa Physiologiae Plantarum. 2014, 36:1867-1878.

19、 Guan Q, Guo X, Han T, Wei M, Jin M, Zen F, Liu L, Li Z, Wang Y, Cheong W, Zhang S*, Jia B. Purification and properties of an organic solvent, detergent, and thermo stable amylopullulanase from Thermococcus kodakarensis KOD1. Process biochemistry. 2013, 48(5-6):878-884.

20、Zhang G, Wang F, Qin J, Wang D, Zhang J, Zhang Y, Zhang S, Pan H. Efficacy assessment of antifungal metabolites from Chaetomium globosum No.05, a new biocontrol agent, against Setosphaeria turcica. Biological Control. 2013, 64:90–98.

21、Han T, Zeng F, Li Z, Liu L, Wei M, Guan Q, Liang X, Peng Z, Liu M, Qin J, Zhang S*, Jia B. Biochemical characterization of a recombinant pullulanase from Thermococcus kodakarensis KOD1. Letters in Applied mMicrobiology. 2013, 57(4):336-343.

22、Jia B, Cheong G, Zhang S*. Multifunctional enzymes in archaea: promiscuity and moonlight. Extremophiles. 2013, 17:193-203.

23、Zhang L, Jia B, Zhuo R, Liu J, Pan H, Baldwin TC, Zhang S*. An Acyl–acyl carrier protein thioesterase gene isolated from wintersweet (chimonanthus praecox), CpFATB, enhances drought tolerance in transgenic tobacco (Nicotiana tobaccum). Plant Molecular Biology Reporter. 2012, 30:433–442.

24、Zhang H, Mu W, Hou Z, Wu X, Zhao W, Zhang X, Pan H, Zhang S*. Biodegradation of nicosulfuron by the bacterium Serratia marcescens N80. Journal of Environmental Science and Health part b-pesticides food contaminants and agricultural wastes. 2012, 47(3):153-160.

25、Cui Z, Wang Y, Bang Phuong Pham, Ping F, Pan H, Cheong G, Zhang S*, Jia B. High level expression and characterization of a thermostable lysophospholipase from Thermococcus kodakarensis KOD1. Extremophiles. 2012, 16: 619-625.

26、Yu G, Liu J, Xie L, Wang X, Zhang S, Pan H. Characterization, cloning, and heterologous expression of a subtilisin-like serine protease gene VlPr1 from Verticillium lecanii. The Journal of Microbiology, 2012, 50(6): 939–946.

27、Zhang S*, Wei Y, Liu J, Yu H, Yin J, Pan H, Baldwin TC. An apoplastic chitinase CpCHT1 isolated from the corolla of wintersweet exhibits both antifreeze and antifungal activities. Biologia Plantarum. 2011, 55 (1): 141-148.

28、Jia B, Linh TLee S, Pham B, Liu J, Pan H, Zhang S, Cheong G. Biochemical characterization of glyceraldehyde-3-phosphate dehydrogenase from Thermococcus kodakarensis KOD. Extremophiles. 2011, 15:337-346.

29、Zhang S*, Wei Y, Yu H, Liu J, Pan H. Wintersweet accumulates apoplastic chitinase with a dual role in petals. Russian Journal of Plant Physiology. 2010, 57(5):670-675.

30、Jia B, Lee S, Bang P, Liu J, Pan H, Zhang S, Cheong G. Oxidized NADH oxidase inhibits activity of an ATP/NAD kinase from a thermophilic archaeon Protein Journal. 2010, 29:609-616.

31、Liang Z, Cheung M, Zhang Q, Lei C, Zhang S, Sun S, Lam HM. A novel simple extracellular leucine-rich repeat (eLRR) domain protein from rice (OsLRR1) enters the endosomal pathway and interacts with the hypersensitive induced reaction protein 1 (OsHIR1). Plant, Cell & Environment. 2009, 32, 1804–1820.

32、Zhang S, Wei Y, Pan H. Transgenic rice plants expressing a novel antifreeze glycopeptide possess resistances to cold and disease. Journal of Bioscience. 2007, 62C: 583-591.

33、Pan H, Wei Y, Xin S, Zhou M, Zhang S. Characterization and biocontrol ability of fusion chitinase in Escherichia coli carrying chitinase cDNA from Trichothecium roseum. Journal of Bioscience. 200661:397-404.

34、Zhang S, Pan H, Wei Y, Bhadauria V. Methylation-based gene silencing selectively occurs in one of the two promoters residing in T-DNA inserted in a retroelement of rice. Russian Journal of Plant Physiology.2006, 53 (2): 266-273.

35、Li D, Zhang S, Liu K, Lu J. Purification and partial characterization of a chitinase from the mycoparasitic fungus Trichothecium roseum. Journal of General and Applied Microbiology. 2004, 50(1): 35-39.

36、He Z, Fu Y, Si H, Hu G, Zhang S, Yu Y, Sun Z. Phosphomannose-isomerase (pmi) gene as a selectable marker for rice transformation via Agrobacterium. Plant Science. 2004, 166: 17-22.

 

 

代表性著作
  1. 1.《Approaches in Bioremediation: The New Era of Environmental Microbiology and NanobiotechnologyChapter 6Fungal nanoparticles formed in saline environments are conducive to soil health and remediation;  Yi Wei, Li-Na Chen, Zi-Yu Zhang, Chi Zhu, Shi-Hong Zhang* Ram Prasad & Elisabet Arandaedit-in-chief), 2018. Springer International Publishing AG.

  2. 2.《Fungi in extreme environments: Ecological and biotechnological significanceChapter 4 Haloalkaliphilic fungi and their roles in the treatment of saline-alkali soil; Wei Yi and Zhang Shi-HongSonia Tiquia-Arashiro & Martin Grubeedit-in-chief),2018. Springer Publishers

  3. 3. Mycoremediation and Environmental Sustainability, Fungal Biology,  Chapter 12: Applications of haloalkaliphilic fungi in mycoremediation of saline-alkali soil. Zhang Shi-Hong and Wei YiRam Prasad  (Editor-in-Chief)2017. p217-233. Springer International Publishing AG. ISBN: 9 78-3-319-68956-2. https://doi.org/10.1007/978-3-319-68957-9_12

  4. 4.《Fungal Applications in Sustainable Environmental Biotechnology, Part I, Chapter 2: The genetic basis of abiotic stress resistance in extremophilic fungi: the genes cloning and application. Zhang Shi-Hong, Diane Purchase (Editor-in-Chief)2016, p29-42. Springer Press. ISBN 978-3-319-42850-5.  http://www.springer.com/gb/book/9783319428505#aboutBook

  5. 5.全国高等农林院校十二五规划教材、普通高等教育农业部十二五规划教材,《农业植物病理学》(第四版),编委,2015中国农业出版社.

  6. 6.林汉明,张世宏,张琦. 《水稻白叶枯病抗性的遗传及改良》,第十章水稻对白叶枯病抗性的机制,2007科学出版社.


代表性授权专利

1. 一种源于极端抗盐碱曲霉的纤维素酶基因及应用;张世宏,李正群,魏毅,陈丽娜,刘少帅,周晓阳,宋妍悦,裴雪;申请号:201610005024.5公告日:2016.01

2. 一种玉米抗病相关基因MR6及其在玉米抗病改良中的应用;张世宏,刘金亮,魏毅,贾保磊,李飞武; 申请号:201310147794.X 公告日:2015.07

3. 一种玉米抗病相关基因MR4及其在玉米抗病改良中的应用;张世宏,魏毅,刘金亮,贾保磊,李飞武; 申请号:201310147765.3 公告日:2015.07

4. 耐碱嗜盐类型的灰绿曲霉菌株及其在环境治理中的应用;魏毅,贾保磊,刘晓丹,张世宏,刘金亮、高文彬; 申请号: 201310162347.1,公告日:2015.07

5. 极端嗜盐曲霉核糖体蛋白基因的克隆及应用;张世宏,谢丽霞,刘晓丹,贾保磊,魏毅,潘洪玉,刘金亮;申请号:201110381937.4 公告日:2012. 06

6. 一种腊梅胚胎发育晚期丰富蛋白的基因及其抗低温应用; 张世宏,谢丽霞,陈宣明,高文,阳晓红,张莉弘,刘金亮, 申请号: 201010155358.3,公告日:2012.05

7. 一种北五味子杂交纯合系的快速繁育方法;张世宏,刘金亮,刘钰才,魏毅,潘洪玉,张莉弘;申请号: 201010157849.1 申请日: 20100428,公告日:2012.05

8. 包含硫酯酶功能域的腊梅基因及其抗旱基因工程应用;张世宏,张莉弘,刘金亮,胡军,于慧美,殷君华,阳晓红,潘洪玉;申请号:200910254000.3,公告日:2012.05

9. 一种腊梅分泌性过氧化物酶的基因、蛋白及其应用;张世宏,阳小红,张莉弘,于慧美,殷君华,刘艺苓,潘洪玉;申请号:200910067456.9 ,公告日:2012.05

10. 一种快速培育蓖麻温敏型隐性核不育单雌系的方法及应用;张世宏,周春莲,魏毅,刘金亮,张鑫生,闫飞,潘洪玉,王勇军;申请号:200810051129.X,公告日:2012.10

 

学术荣誉与科技成果

主持完成的“微生物-纳米整合”治理盐碱地技术(MiNIT)在中国生产力学会和中国植物营养与肥料学会组织的国家级成果评定中被评为国际先进水平。

 

 

 

 

 

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地址:长春市西安大路5333号

邮编:130062

电话:0431-87836260

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