张世宏

发布时间:2015-11-11

博士,教授,学科带头人,博士生导师

  

概况:

吉林大学分子植物病理学与植物抗逆基因工程学科带头人,吉林省作物基因工程重点实验室主任,美国University of Massachusetts马萨诸塞大学英国University of Wolverhampton(伍尔弗汉普顿大学),以及香港中文大学合作教授。

2003年博士毕业于中国农业大学农业部分子植物病理学重点实验室。2006年加盟吉林大学植物科学学院,先后任植物科学学院第一、二届学术委员会主任,主导组建了植物科学学院学术与科研平台,为学院的科学研究、国内外合作与交流、人才培养等营造了良好的氛围。

    主要研究分子植物病理学与植物抗逆境基因工程、真菌分子遗传与微生物基因工程。先后主持承担国家植物转基因重大专项、农业部植保行业科技专项、国家科技重点专项、国家自然科学基金面上项目等30多项;发表研究论文100多篇,在AEMBB、MPP等国际知名期刊发表研究型SCI论文30余篇,获得国家授权发明专利20多项;近10年来承担并讲授从本科生至博士生的多门主干课程,培养出多名青年才俊,其中40多名硕士、博士毕业生和博士后研究人员已活跃在高校或科研单位,为祖国的教育和科研事业发挥着重要作用。

  

  

工作经历

2006.06-            吉林大学                      学科带头人、教授、博士生导师

2009.01-           香港中文大学                   合作教授

2008.01-            美国马萨诸塞大学              合作教授

2007.01- 2015.12    英国伍尔弗汉普顿大学          合作教授

2010.08-2010.11    美国密西根大学、麻省州立大学   高级访问学者

2011.12- 2012.06    美国普渡大学                  高级访问学者

2005.06 - 2006.06   香港中文大学                  引进大陆优秀人才计划研究员

2003.07 2005.06  农业生物技术国家重点实验室     博士后

  

主要学术兼职

美国微生物学会高级会员,欧洲植物病理学会会员,中国植物病理学会会员,中国青年植物病理学会副主任(2008-2014),《植物学研究》编委,教育部科技论文在线特聘专家

特邀审稿杂志:Cellular Microbiology,Molecular Microbiology,Applied Environmental Microbiology,Starch, World Journal of Microbiology& Biotechnology, Planta, Applied Biochemistry and Microbiology,Transgenic Research, Plos One, FEMS Microbiology Letters,International Journal of Biological Macromolecules.

教学情况

本科生必修课程:《农业植物病理学》

硕士研究生课程:《分子植物病理学》、《植物基因工程原理》

博士研究生课程:《高级植物生理生化》

主要研究方向

1.分子植物病理学与植物抗逆境基因工程

2.真菌分子遗传与微生物基因工程

近期主持的主要科研项目:

  

1.国家重点研发计划项目,2016YFD0300700,粮食主产区主要病虫草害发生及其绿色防控关键技术(吉林省水稻病虫害绿色防控关键技术,2016.01-2020.12,主持人。

2.国家自然科学基金面上项目,31671972,稻瘟菌Lon酶切修饰的C3HC-锌指蛋白在线粒体致病途径中的作用机理,2017.01-2020.12,主持人

3.国家自然科学基金面上项目,31670141,蛋白质-酪氨酸磷酸酶在调控稻瘟菌致病与抗氧化过程中的分子机理,2017.01-2020.12,第一参加人

4.江苏省校企科技合作项目,3R116B896202,盐城滩涂盐碱地的纳米-生物修复与开发,2016.01-2017.12,主持人

5.农业部转基因重大专项,2011ZX08009-001,抗病虫、抗除草剂转基因玉米新品种培育,2012.01-2016.12,子课题主持人

6.农业部植保行业科技项目,201203014,粮食作物基因对基因病害的抗病品种布局技术研究示范,2012.01-2016.12,子课题主持人

7.国家自然科学基金面上项目,31171794BBP/SF1剪接因子参与调控稻瘟菌侵染性菌丝扩展的机理研究,2012.01-2015.12。,主持人

8.教育部高等学校博士学科点专项科研基金(博导类),201000611100 74,稻瘟菌染色质共价修饰对致病力变异的调控研究,2010.1- 2013.12,主持人

9.国家自然科学基金面上项目,30871607,中国东北地区极端低温对稻瘟病菌的选择与致变效应,2009.1-2011.12,主持人

10.农业部转基因重大专项,植物抗逆基因与逆境诱导性启动子的克隆与功能验证,2009ZX08009-062B2009.1-2010.12,子课题主持人

11.花粉管伸长与真菌菌丝生长的分子共性研究, UMassAmhers-JLU Heping长期合作项目,主持人

12.吉林大学引进人才建设专项经费,植物花器抗冻的物质基础和模型的建立,2006-2009,主持人

13.香港引进大陆优秀人才计划项目Functional analysis of rice blast disease resistance relatedgenesIn Hong Kong),2005-2008,主持人

 

代表性专利:

1.一种玉米抗病相关基因MR6及其在玉米抗病改良中的应用;张世宏,刘金亮,魏毅,贾保磊,李飞武;申请号:201310147794.X公告日:2015.07

2.一种玉米抗病相关基因MR4及其在玉米抗病改良中的应用;张世宏,魏毅,刘金亮,贾保磊,李飞武;申请号:201310147765.3公告日:2015.07

3.耐碱嗜盐类型的灰绿曲霉菌株及其在环境治理中的应用;魏毅,贾保磊,刘晓丹,张世宏,刘金亮、高文彬;申请号: 201310162347.1,公告日:2015.07

4.极端嗜盐曲霉核糖体蛋白基因的克隆及应用;张世宏,谢丽霞,刘晓丹,贾保磊,魏毅,潘洪玉,刘金亮;申请号:201110381937.4公告日:2012. 06

5.一种腊梅胚胎发育晚期丰富蛋白的基因及其抗低温应用;张世宏,谢丽霞,陈宣明,高文,阳晓红,张莉弘,刘金亮,申请号: 201010155358.3,公告日:20120530

6.一种北五味子杂交纯合系的快速繁育方法;张世宏,刘金亮,刘钰才,魏毅,潘洪玉,张莉弘;申请号: 201010157849.1申请日:20100428,公告日:20120530

7.包含硫酯酶功能域的腊梅基因及其抗旱基因工程应用;张世宏,张莉弘,刘金亮,胡军,于慧美,殷君华,阳晓红,潘洪玉;申请号:200910254000.3,公告号:101870983B,公告日:20120530

8.一种腊梅分泌性过氧化物酶的基因、蛋白及其应用;张世宏,阳小红,张莉弘,于慧美,殷君华,刘艺苓,潘洪玉;申请号:200910067456.9,公告日:20120530

9.一种快速培育蓖麻温敏型隐性核不育单雌系的方法及应用;张世宏,周春莲,魏毅,刘金亮,张鑫生,闫飞,潘洪玉,王勇军;申请号:200810051129.X,公告日:20121017

  

著作:

1.Fungal Applications in Sustainable Environmental Biotechnology, Part I, Chapter 2: The genetic basis of abiotic stress resistance in extremophilic fungi: the genes cloning and application.Zhang Shi-Hong, Diane Purchase (Editor-in-Chief)2016. SpringerPress. ISBN 978-3-319-42850-5. http://www.springer.com/gb/book/9783319428505#aboutBook

2.参编全国高等农林院校“十二五”规划教材、普通高等教育农业部“十二五”规划教材,《农业植物病理学》(第四版),2015,中国农业出版社。

3.林汉明,张世宏,张琦.《水稻白叶枯病抗性的遗传及改良》,第十章水稻对白叶枯病抗性的机制,2007,科学出版社.

  

Professor Dr. Shi-Hong Zhang

Director ofthe KeyLaboratory for Plant Molecular Biology

Shi-Hong Zhang got his Ph.D degree from China Agricultural University (CAU) in 2003. Then, he did a 2-years post-doc in the State Key Laboratory of Agricultural Biotechnology, CAU. He worked in The Chinese University of Hong Kong (CUHK)for2 years, and thenjoined the College of Plant Sciences, Jilin University China,as afull-time professor.

Research in the Zhang Labis focused on understanding molecular mechanisms of fungal pathogenicity tocrops, with the ultimate goal of developing improved methods for management ofRICE and MAIZEdiseases. We also focus on environmental fungi with potential application values: their identification, genetics and applications in agricultural practice.

Research Directions:

1. Molecular plant pathology and genetic engineeringfor crops multi-stress resistance;

2. Fungal molecular genetics and genetic engineering.

  

  

Selected Publications(*通讯作者)

2016-2017年

   Feiwu LiLikun LongWei YanCongcong LiJunfengXuYunjunLiushihongZhang Email author

Development of an Event-Specific Detection Method for Genetically Modified Maize IE034 by Quantitative Real-Time PCRFood Analytical MethodsJune 2017, Volume 10, Issue 6,pp 17271735 |

  Xiao Cuiab, Yi Weia, Xiang-Li Xiea, Li-Na Chena, Shi-Hong Zhanga,

Mitochondrial and peroxisomal Lon proteases play opposing roles in reproduction and growth but co-function in the normal development, stressresistance and longevity of Thermomyces lanuginosus. Fungal Genetics and Biology, 103 (2017) 42–54

    Xue Pei, Junqi Zhao, Pengli Cai, Wenliang Sun, Jie Ren, Qiaqing Wu, Shihong Zhang, Chaoguang Tian*. Heterologous expression of a GH3 ß-glucosidase from Neurospora crassa in Pichia pastoris with high purity and its application in the hydrolysis of soybean isoflavone glycosides.Protein Expression and Purification. 119(2016):75-84

  

  

2015

Liu Y, Xie L, Liang X,Zhang S*.CpLEA5, the late embryogenesis abundant protein gene fromChimonanthus praecox, possesses low temperature and osmotic resistances in prokaryote and eukaryotes. International Journal of Molecular Sciences. 2015, 16, 26978–26990.

Pei X, Fan F, Lin L, Chen Y, Sun W,Zhang S*, Tian C*. Involvement of the of the adaptor protein 3 complex in lignocellulase secretion inNeurospora crassa revealed by comparative genomic screening. Biotechnology Biofuels. 2015, 8: 124.

Pei X, Zhao J, Cai P, Sun W, Ren J, Wu Q,Zhang S, Tian C *. Heterologous expression of a GH3 ß-glucosidase fromNeurospora crassa inPichia pastoris with high purity and its application in the hydrolysis of soybean isoflavone glycosides. Protein Expression and Purification. 2015, 119(2016):75-84.

Liu X, Wei Y, Zhou X, Pei X,Zhang S*.Aspergillus glaucusaquaglyceroporin geneglpF confers high osmosis tolerance in heterologous organisms.Applied and Environmental Microbiology. 2015, Oct, 81(19): 6926-6937.

Liang X, Liu Y, Xie L, Liu X, Wei Y, Zhou X,Zhang S*. A ribosomal protein AgRPS3aE from halophilicAspergillus glaucus confers salt tolerance in heterologous organisms. International Journal of Molecular sciences. 2015, 16(2), 3058-3070.

Liang X, Liu J, Liu S, Liang X,Zhang S*. Alternatively splicedSMNorthologue inMagnaporthe oryzae is required for stress resistance and disease development. European Journal of Plant Pathology. 2015, 142:427-439.

Cui X, Wei Y, Wang Y, Zheng Y, Li J, Wong F, Liu S, Yan H, Jia B, Liu J,Zhang S*. Proteins interacting with mitochondrial ATP-dependent Lon protease (MAP1) inMagnaporthe oryzae are involved in rice blast disease. Molecular Plant Pathology. 2015, 16(8):847-859.

Li J, Liang X, Wei Y, Liu J, Lin F,Zhang S*. An ATP-dependent protease homolog ensures basic standards of survival and pathogenicity forMagnaporthe oryzae. European Journal of Plant Pathology. 2015, 141(4):703-716.  

2014

Li F, Yan W, Long L, Qi X, Li C,ZhangS*. Development and application of loop-mediated isothermal amplification assays for rapid visual detection ofcry2Ab andcry3A genes in genetically-modified crops. International Journal of Molecular Sciences. 2014, 15, 15109-15121.

Liu X, Xie L, Wei Y, Zhou X, Jia B, Liu J,Zhang S*. Abiotic stress resistance, a novel moonlighting function of ribosomal protein RPL44 in halophilicAspergillus glaucus. Applied and Environmental Microbiology. 2014, 80(14):4294-4300.

Li J, Jia B, Liang X, Liu J, Wang Y, Liang X, Yan H, Wang Y,Zhang S*. An adenosine kinase in apoplastic location is involved inMagnaporthe oryzae cold acclimation. Journal of Basic Microbiology. 2014, 54(4):269-277.

Wang F, Liu J, Li J,Zhang S, Pan H*. Functional analyses of the maizeCKS2 gene promoter in response to abiotic stresses and hormonesActa Physiologiae Plantarum. 2014, 36:1867-1878.

 

2013

Guan Q, Guo X, Han T, Wei M, Jin M, Zen F, Liu L, Li Z, Wang Y, Cheong W,Zhang S*, Jia B. Purification and properties of an organic solvent, detergent, and thermo stable amylopullulanase fromThermococcus kodakarensis KOD1. Process biochemistry. 2013, 48(5-6):878-884.

Zhang G,Wang F, Qin J, Wang D, Zhang J, Zhang Y,Zhang S, Pan H. Efficacy assessment of antifungal metabolites fromChaetomium globosum No.05, a new biocontrol agent, againstSetosphaeria turcica. Biological Control. 2013, 64:90–98.

Han T, Zeng F, Li Z, Liu L, Wei M, Guan Q, Liang X, Peng Z, Liu M, Qin J,Zhang S*, Jia B. Biochemical characterization of a recombinant pullulanase fromThermococcus kodakarensis KOD1. Letters in Applied mMicrobiology. 2013, 57(4):336-343.

Jia B, Cheong G,Zhang S*. Multifunctional enzymes in archaea: promiscuity and moonlight. Extremophiles. 2013, 17:193-203.

 

2012

Zhang H, Mu W, Hou Z, Wu X, Zhao W, Zhang X, Pan H,Zhang S*. Biodegradation of nicosulfuron by the bacteriumSerratia marcescensN80.Journal of Environmental Science and Health part b-pesticides food contaminants and agricultural wastes. 2012, 47(3):153-160.

Cui Z, Wang Y, Bang Phuong Pham, Ping F, Pan H, Cheong G,Zhang S*, Jia B. High level expression and characterization of a thermostable lysophospholipase fromThermococcus kodakarensis KOD1. Extremophiles. 2012, 16: 619-625.

Yu G, Liu J, Xie L, Wang X,Zhang S, Pan H. Characterization, cloning, and heterologous expression of a subtilisin-like serine protease geneVlPr1 fromVerticillium lecanii. The Journal of Microbiology, 2012, 50(6): 939–946.

Zhang L, Jia B, Zhuo R, Liu J, Pan H, Baldwin TC,Zhang S*. An Acyl–acyl carrier protein thioesterase gene isolated from wintersweet (chimonanthus praecox), CpFATB, enhances drought tolerance in transgenic tobacco (Nicotiana tobaccum). Plant Molecular Biology Reporter. 2012, 30:433–442.

 

2011

Zhang S*, Wei Y, Liu J, Yu H, Yin J, Pan H, Baldwin TC. An apoplastic chitinase CpCHT1 isolated from the corolla of wintersweet exhibits both antifreeze and antifungal activities. Biologia Plantarum. 2011, 55 (1): 141-148.

Jia B, Linh TLee S, Pham B, Liu J, Pan H,Zhang S, Cheong G. Biochemical characterization of glyceraldehyde-3-phosphate dehydrogenase fromThermococcus kodakarensis KOD. Extremophiles. 2011, 15:337-346.

 

2010

Zhang S*, Wei Y, Yu H, Liu J, Pan H. Wintersweet accumulates apoplastic chitinase with a dual role in petals. Russian Journal of Plant Physiology. 2010, 57(5):670-675.

Jia B, Lee S, Bang P, Liu J, Pan H,Zhang S, Cheong G. Oxidized NADH oxidase inhibits activity of an ATP/NAD kinase from a thermophilic archaeon. Protein Journal. 2010, 29:609-616.

 

2010年之前发表的SCI论文

Liang Z, Cheung M, Zhang Q, Lei C,Zhang S,Sun S, Lam HM. A novel simple extracellular leucine-rich repeat (eLRR) domain protein from rice (OsLRR1) enters the endosomal pathway and interacts with the hypersensitive induced reaction protein 1 (OsHIR1). Plant, Cell & Environment. 2009, 32, 1804–1820.

Zhang S, Wei Y, Pan H. Transgenic rice plants expressing a novel antifreeze glycopeptide possess resistances to cold and disease. Journal of Bioscience. 2007, 62C: 583-591.

Pan H, Wei Y, Xin S, Zhou M,Zhang S. Characterization and biocontrol ability of fusion chitinase inEscherichia colicarrying chitinase cDNA fromTrichothecium roseum. Journal of Bioscience. 200661:397-404.

Zhang S, Pan H, Wei Y, Bhadauria V. Methylation-based gene silencing selectively occurs in one of the two promoters residing in T-DNA inserted in a retroelement of rice. Russian Journal of Plant Physiology.2006, 53 (2): 266-273.

Li D,Zhang S, Liu K, Lu J. Purification and partial characterization of a chitinase from the mycoparasitic fungusTrichothecium roseum. Journal of General and Applied Microbiology. 2004, 50(1): 35-39.

He Z, Fu Y, Si H, Hu G,Zhang S, Yu Y, Sun Z. Phosphomannose-isomerase (pmi) gene as a selectable marker for rice transformation via Agrobacterium. Plant Science. 2004, 166: 17-22.

 

  

 

  

 

本实验室常年招收对植物病理学真菌分子遗传植物分子生物学、植物和微生物互作等感兴趣的访问学者、博士后、研究生(博/硕士),或合同制研究助理。欢迎有志青年到本实验室学习交流。

Young and ambitiousscientists at home and abroad, WELCOME YOU ALL!

 

   

  

通讯地址:

吉林省长春市西安大路5333

吉林大学植物科学学院邮编130062

Email:  zhang_sh@jlu.edu.cn

办公电话:0431-87835708; 87836274

传真:0431-87835708

实验室电话:0431-87836277